Failure of implantation and biochemical pregnancy: Dr. Nathan Zhang from IVF USA discusses assisted reproduction

2024-03-18 20:28:00，visits： 321

Pregnancy is a joyous time for every woman, signifying the completeness and happiness of a family. However, sometimes unexpected situations are unavoidable. In such instances, rather than being disheartened and blaming oneself, it's important to seek medical help promptly, receive professional advice and examinations, and restore physical and mental well-being for subsequent attempts.

Today, we'll discuss two professional terms related to the process of conception: "failure of implantation" and "biochemical pregnancy."

1. Failure of Implantation:

Failure of implantation occurs when, after the sperm and egg form a fertilized egg, it fails to establish a close connection with the uterine lining upon reaching the uterus. This process is silent during the menstrual cycle, so the symptoms of implantation failure are not obvious. If the embryo fails to implant successfully, the uterine lining sheds, resulting in a normal menstrual cycle.

Various factors can contribute to implantation failure, including abnormalities in the uterine environment, embryo defects, emotional factors, environmental factors, diseases, and more. Therefore, undergoing a physical examination before deciding on egg freezing or in vitro fertilization (IVF) is a crucial step. These examinations can provide comprehensive insights into the condition of the ovaries, providing necessary information for subsequent egg freezing.

2. Biochemical Pregnancy:

Biochemical pregnancy occurs when the embryo has started to implant, but due to certain reasons, such as environmental or internal factors, the embryo cannot be compatible with the uterine lining. This leads to a transient increase in β-HCG levels in the blood or urine, followed by the pregnancy not progressing to the stage where it can be diagnosed by ultrasound. Biochemical pregnancy is often difficult to detect, and women may mistake it for a delayed menstrual cycle.

The factors that cause biochemical pregnancy are similar to those of implantation failure, including embryo issues, uterine environment problems, ovarian luteal function issues, and more.

Regarding this issue, we consulted Dr. Nathan Zhang, a doctor in the field of assisted reproduction, a graduate of the University of Pennsylvania School of Medicine, and the founder of IVF USA. He pointed out that a woman's age is a common factor leading to both conditions. As age increases, the probability of embryo chromosomal abnormalities and the miscarriage rate also increase. In women over 42 years old, more than 80% of embryos have chromosomal abnormalities. After the age of 35, the natural miscarriage risk significantly increases, and for women over 40, the natural pregnancy rate is less than 5%, making pregnancy considerably challenging for older mothers.

We understand that the process of conception and pregnancy is filled with anticipation and uncertainty, but with scientific methods and professional team support, you will be more confident to face this journey. Wherever you are, we are willing to work with you to embrace a brighter future of reproduction. If you have any needs or questions about egg freezing technology, please feel free to contact us. Dr. Nathan Zhang will personally provide you with professional advice and support to help you develop a personalized fertility plan. Currently, IVF USA provides services such as egg freezing and IVF for those in need, with operations expanded to regions outside the United States, including Japan, Thailand, Mexico, Taiwan, Hong Kong, among others, collaborating closely with top IVF doctors globally.