Recurrent Miscarriage: Essential Knowledge You Must Know! Can it be Resolved through IVF in the USA?

2024-01-10 20:06:10，visits： 419

Mrs. Z, a 35-year-old married woman, has experienced three miscarriages. Despite undergoing various examinations, the exact cause remains elusive. Only those preparing to become mothers truly understand the hardship of such an experience. There are multiple reasons for miscarriage, let's explore the types and potential causes of miscarriage together.

Miscarriages are primarily categorized into spontaneous miscarriage and recurrent miscarriage.

Spontaneous miscarriage refers to a naturally occurring miscarriage, typically happening within 28 weeks of pregnancy. Early miscarriage occurs before 12 weeks, while late miscarriage occurs between 12 and 28 weeks (excluding the 28th week). According to medical statistics, about 75% of all pregnancies end in spontaneous miscarriage.

Recurrent miscarriage is diagnosed when two or more spontaneous miscarriages occur consecutively, representing a relatively challenging form of infertility that requires careful attention. The causes of miscarriage are diverse, and only through comprehensive examinations, consultations, and the formulation of a preconception plan can the chances of pregnancy be improved.

Immunological Factors

Statistics indicate that 6% to 14% of families trying to conceive in China have experienced recurrent miscarriages or struggled with infertility. Clinical studies suggest that over 50% of recurrent miscarriage cases are due to immunological pregnancy disorders. Pregnancy, much like allogeneic transplantation, involves a complex and unique immunological relationship between the embryo and the mother. If there is an immune mismatch between the mother and the fetus, the mother's body may reject the embryo, leading to miscarriage. For women with recurrent miscarriages and no detected abnormalities in immune checks, the lack of certain antibodies may prevent the mother from protecting the embryo, resulting in miscarriage.

Embryonic Abnormalities

Abnormalities in the number or structure of embryonic chromosomes are the most common causes of recurrent miscarriage. Environmental factors, radiation, drugs, or natural variations can lead to genetic abnormalities in the embryo. Dr. Nathan Zhang, a medical doctor and expert in the field of assisted reproduction at the University of Pennsylvania, recommends using the third-generation IVF technology in the USA. This involves dual techniques, PGS and PGD, to test the chromosomes of the fetus, reducing the risk of miscarriage. Therefore, if the cause of miscarriage is embryonic abnormalities, trying IVF technology may yield different reproductive outcomes.

Male Semen Abnormalities

Miscarriage is not only closely related to the female body but may also be related to factors such as the volume of male semen, sperm concentration, the percentage of a/b-grade sperm, and the percentage of deformed sperm, triggering recurrent miscarriages.

Luteal Phase Insufficiency

Pre-pregnancy luteal phase insufficiency is characterized by a shortened menstrual cycle, premenstrual spotting, normal or slightly excessive menstrual flow. These symptoms are often not easily detected before recurrent miscarriages occur and sometimes require basal body temperature measurements, plasma hormone level measurements, or diagnostic curettage for diagnosis.

Additional Factors: Multiple Abortions, Infections, Uterine or Cervical Lesions, Internal Diseases, Environmental, and Unhealthy Lifestyle Habits

For women planning to conceive, it is advisable to identify the type of miscarriage early and find specific causes for targeted treatment. If assisted reproductive methods are needed, it is recommended to take action early and remain confident! Dr. Nathan Zhang, as an expert in the field of assisted reproduction, will personally provide you with professional guidance and support to ensure your egg freezing journey goes smoothly. Currently, IVF USA provides services such as American egg freezing, American IVF, and third-party assisted reproduction to those in need. Our services extend beyond the USA to include Japan for IVF and egg freezing, Thailand for IVF and egg freezing, as well as Mexico, Taiwan, Hong Kong, and other regions. We collaborate with top IVF doctors globally to ensure your IVF journey is smooth and obstacle-free.