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Frozen Embryo Transfer (FET) is a critical step for the success of IVF. However, prospective parents may encounter several potential physiological obstacles during this process.
The endometrium is the "soil" for embryo implantation. Endometrial issues are a common cause of transfer failure.
1. Thin Endometrium: Studies show that insufficient endometrial thickness can reduce pregnancy rates. Doctors will typically try various medications to thicken the endometrium. Even if the lining remains thin, the doctor might decide to proceed with the transfer, as a thin lining does not absolutely exclude the possibility of pregnancy. However, if the condition is suboptimal, they might choose to cancel the cycle to ensure the best pregnancy preparation conditions.
2. Intrauterine Fluid Interference: Fluid accumulation produced by endometrial cells can sometimes accumulate in the uterine cavity. If the fluid is caused by hydrosalpinx, surgical treatment is required before transfer. The doctor must carefully evaluate whether the fluid affects the implantation window and may postpone the cycle.
The timing of embryo transfer (the "implantation window") is crucial; even minor deviations can lead to implantation failure.
3. Premature Ovulation: Early ovulation changes the timing of progesterone production in the body, which, in turn, affects the ideal implantation window. To prevent premature ovulation, doctors typically use medication for intervention to precisely control progesterone production, ensuring the embryo is implanted at the scheduled time.
4. Improper Transfer Timing: The latest research confirms that the implantation window may shift earlier or later for a small proportion of women. Through advanced tests like the Endometrial Receptivity Assay (ERA), doctors can determine the precise implantation window and adjust the embryo transfer time for the US and Mexico IVF cycle accordingly, achieving personalized transfer.
5. Vaginal bleeding or mild discomfort after transfer is usually a normal physiological reaction. However, any concerns or persistent discomfort should be promptly discussed with the attending physician. Furthermore, selecting high-quality embryos is an essential guarantee for reducing implantation failure.
Facing these potential issues, individualized medical intervention and targeted treatment plans are key to ensuring the success of frozen embryo transfer. If you are planning an IVF journey, particularly considering US and Mexico IVF services, and wish to have a clear understanding of the potential issues during the transfer process, the IVF USA team can provide you with professional support.

The IVF USA team, founded by Dr. Nathan Zhang, has been providing overseas assisted reproductive consulting services for over a decade, offering US egg freezing, US IVF, and third-party assisted reproductive services to those in need. With nearly 20 years of deep expertise in the overseas assisted reproductive field, IVF USA, driven by diverse and personalized reproductive needs, strategically expanded into the Mexican market early on, becoming the authorized agent for Power Fertility Center Mexico (POWER IVF) in China. Dr. Nathan Zhang's services currently extend beyond the US to include IVF and egg freezing in Mexico, Japan, and Thailand, as well as Taiwan and Hong Kong. To ensure your pregnancy preparation journey is smooth and unimpeded, allow a professional team to provide you with comprehensive support using their experience and technology, and jointly move towards a wonderful future of having a healthy baby.