Even if both parents are chromosomally normal, can they still have a baby with abnormalities? The answer from IVF USA and IVF in Mexico

2025-10-17 10:54:46，visits： 122

 

Over the past two years, Mrs. Wang has experienced multiple pregnancies, yet each time ended in miscarriage due to chromosomal abnormalities in the fetus. Her story is not uncommon. Many couples face similar situations—both partners’ chromosomal tests are normal, yet the embryo still shows abnormalities. Why does this happen?

 

Chromosomal abnormalities refer to changes in the number or structure of chromosomes, such as deletions, duplications, or translocations. Even when both parents have normal chromosomes, errors may occur during cell division or DNA replication in the early stages of embryo formation. In natural conception, chromosomal abnormalities are among the leading causes of early miscarriage. As women age, egg quality declines, and the risk of chromosomal mis-segregation increases.

 

Although Mrs. Wang is relatively young and both she and her husband are healthy, she could not understand why the embryos repeatedly showed chromosomal issues. In fact, even when parents’ chromosomes are normal, environmental factors can play a role—such as radiation exposure, chemicals, or even chronic stress. These can all increase the likelihood of errors during cell division or DNA replication.

 

According to IVF USA, maternal age remains one of the core risk factors for chromosomal abnormalities in embryos. As women age, ovarian function declines, making chromosomal errors during egg division more likely. Male age can also impact sperm DNA integrity. Therefore, even if both partners’ genetic tests are normal, chromosomal abnormalities can still appear in the embryos.

 

To address this issue, IVF USA adopts IVF-PGT technology (Preimplantation Genetic Testing). This advanced procedure involves genetic screening (PGD/PGS) before embryo transfer to identify chromosomally normal embryos for implantation. This approach significantly increases the success rate of pregnancy while reducing the risk of miscarriage caused by chromosomal abnormalities.

 

Dr. Nathan Zhang points out that IVF-PGT is particularly beneficial for women with a history of chromosomal abnormalities, recurrent miscarriages, or advanced maternal age. By using this technology, doctors can select the healthiest embryos, giving patients a better chance at a successful pregnancy and healthy birth.

 

Since each patient’s physical condition varies, IVF USA conducts comprehensive medical assessments to create customized IVF-PGT treatment plans. By evaluating ovarian function, hormone levels, and uterine condition, the team designs a tailored strategy that not only improves success rates but also minimizes unnecessary risks.

Founded by Dr. Nathan Zhang, IVF USA has been engaged in international reproductive consultation for over a decade, offering U.S. egg freezing, IVF, and third-party reproductive services. With nearly 20 years of experience in global assisted reproduction, IVF USA has strategically expanded into the Mexico market to meet diverse reproductive needs, becoming the official China representative of Power Fertility Center (POWER IVF) in Mexico. Today, Dr. Nathan Zhang’s services extend beyond the U.S. to include IVF and egg freezing in Mexico, Japan, Thailand, Taiwan, and Hong Kong. With the support of Dr. Zhang and his professional team, many families have fulfilled their dream of having a child. For those facing similar challenges, IVF USA stands ready to accompany you on the journey toward welcoming a healthy baby.