Can Parents with Normal Chromosomes Have a Baby with Abnormalities? US and Mexico IVF Explains

2025-07-27 10:18:18，浏览量： 3次

Over the past two years, Ms. Wang eagerly anticipated new life multiple times, but each instance resulted in miscarriage due to fetal chromosomal abnormalities. Her experience isn't uncommon; in fact, many couples face similar confusion: Why are both our chromosomes normal, yet the embryo still develops chromosomal abnormalities? For families undergoing pregnancy preparation, this is undoubtedly a huge challenge.

Chromosomal abnormalities refer to atypical numbers or structures of chromosomes, such as deletions, duplications, or translocations. This can occur early in embryonic development, even if the parents' chromosomes are entirely normal. In natural pregnancies, embryonic chromosomal abnormalities are a primary cause of miscarriage, especially for older women, where this risk is higher. As age increases, egg quality declines, raising the probability of chromosomal segregation errors, which can lead to abnormalities.

Ms. Wang is not old, and both she and her husband are in good health, so she couldn't understand why the embryo repeatedly had chromosomal issues. In truth, even with normal parental chromosomes, during embryo formation, the fusion of sperm and egg can be influenced by various .

factors, such as environmental radiation, chemical exposure, or even daily life stress. All these factors can cause unexpected errors in embryonic chromosome replication or division.From Dr. Nathan Zhang's perspective at IVF USA, age is a significant factor influencing embryonic chromosomal abnormalities. As women age, their ovarian function gradually declines, and the risk of chromosomal errors during egg division increases. Male age also affects sperm quality, particularly the integrity of sperm DNA. Therefore, even if both partners show no signs of chromosomal abnormalities in physical examinations, chromosomal abnormalities can still appear in their embryos.

To help patients like Ms. Wang, IVF USA utilizes advanced IVF-PGT (Third-Generation IVF) technology. The core of this technique involves preimplantation genetic diagnosis or screening (PGD/PGS) of embryos before transfer, allowing for the selection of chromosomally normal embryos for implantation. This method not only significantly boosts pregnancy success rates but also effectively lowers the risk of miscarriage caused by chromosomal abnormalities.Dr. Nathan Zhang explains that IVF-PGT technology is especially suitable for women with a history of chromosomal abnormalities, recurrent miscarriages, and advanced maternal age. Through this technology, doctors can precisely select the healthiest embryos, giving patients a greater chance of successful pregnancy and delivering a healthy baby.

Every patient's physical condition is unique. Dr. Nathan Zhang's IVF USA team, established by him and providing overseas assisted reproductive consulting services for over a decade, offers US egg freezing, US IVF, and third-party assisted reproduction services to those in need. With nearly 20 years of deep expertise in the field of overseas assisted reproduction, IVF USA, driven by diverse and personalized reproductive needs, strategically expanded into the Mexican market early on, becoming the authorized agent for Power Fertility Center Mexico (POWER IVF) in China. Dr. Nathan Zhang's services currently extend beyond the US to include IVF and egg freezing in Mexico, Japan, and Thailand, as well as Taiwan and Hong Kong. We understand your desire for a healthy baby. IVF USA will provide you with scientific and rigorous assessment and support to help you achieve your successful reproductive journey.