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Whether it's for egg freezing or IVF, ovarian stimulation is an indispensable step. With numerous stimulation protocols available, many women feel confused when choosing, unsure whether to opt for the long protocol, short protocol, micro-stimulation protocol, or antagonist protocol. Today, we'll delve into this topic to help you better understand the ovarian stimulation process and the applicability of different protocols.
The Scientific Principle of Ovarian Stimulation: Activating "Sleeping" Follicles
Ovarian stimulation is performed under strict medical supervision. It involves using ovarian stimulation drugs to induce follicles that would otherwise cease development to continue growing until maturity. Subsequently, doctors manually retrieve these eggs for in vitro freezing or fertilization. It's worth noting that ovarian stimulation does not reduce a woman's ovarian reserve of follicles. Its role is to "awaken" those eggs that would naturally degenerate in a single cycle, allowing these "discarded" eggs to become viable, thereby increasing the number of retrievable eggs.
Analysis of the Applicability of Different Stimulation Protocols
Long Protocol: This is currently a more commonly used protocol, involving a longer period of downregulation to control ovarian stimulation, lasting approximately 1 month. It is primarily for women with normal ovarian reserve function.
Short Protocol: This protocol is shorter in duration but slightly stronger in stimulation, lasting approximately 10-15 days. It is suitable for older women with suboptimal ovarian function.
Micro-stimulation Protocol: This is a gentler stimulation protocol without a downregulation process, using smaller doses of ovarian stimulation drugs, lasting approximately 8-10 days. It is suitable for patients with poor ovarian response, polycystic ovary syndrome, and those who previously experienced severe ovarian hyperstimulation syndrome.
Antagonist Protocol: As a traditional stimulation protocol, the antagonist protocol involves a shorter medication period, lower cost, and generally ideal results, lasting approximately 7-15 days. It is primarily suitable for women with polycystic ovary syndrome, poor ovarian reserve function, and those who had an unsatisfactory response to previous stimulation protocols. In the United States, the antagonist protocol is more commonly used.
When choosing an ovarian stimulation protocol, the most important thing is not to get bogged down by the specific protocol name, but to find the right doctor and clinic for you. Dr. Nathan Zhang points out that even within the same stimulation protocol, there can be differences in medication dosage, drug combinations, and egg retrieval timing among different doctors. These seemingly subtle differences are often the key factors determining the success rate of egg freezing or IVF. Therefore, spending time finding an experienced, specialized doctor and a trustworthy clinic is far more important than simply researching specific stimulation protocols.
The IVF USA team, founded by Dr. Nathan Zhang, has been providing overseas assisted reproductive consulting services for over ten years, offering US egg freezing, US IVF, and third-party assisted reproductive services to those in need. With nearly 20 years of deep expertise in the overseas assisted reproductive field, IVF USA proactively entered the Mexico market, driven by diverse and personalized reproductive needs, becoming the authorized agent for Power Fertility Center Mexico POWER IVF in China. Currently, Dr. Nathan Zhang's business has expanded beyond the US to include IVF and egg freezing in Mexico, Japan, and Thailand, as well as Taiwan and Hong Kong. Dr. Nathan Zhang and his team are dedicated to helping every patient achieve their dream of having a healthy baby. IVF USA looks forward to partnering with you to welcome new life.